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Amyloidosis: the different aspects of wide range of diseases "similar in their differences"
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Academic year 2019/2020
- Teaching staff
- Prof.ssa Elena Tamagno
Prof.ssa Michela Guglielmotto (Titolare del corso) - Teaching period
- Da definire
- Type
- Seminario
- Credits/Recognition
- 1
- Delivery
- A distanza
- Language
- Inglese
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Sommario del corso
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Course objectives
Amyloidosis is not a single disease but a series of diseases in which there is extra-cellular deposition of a protein, which although it may be derived from different and unrelated sources, folds into a pleated sheet. There have recently been significant advances in elucidating the pathogenesis and in the treatment of this group of disorders. By identifying the source of precursor protein, treatment is aimed at eliminating or reducing the extent of deposition and is tailored for each patient. Early diagnosis is required for the optimal effect of treatment on patient survival and quality of life. Although the pathological chemical modifications of proteins are in common, amyloidosis is a whole of different diseases. This course is focus on the description of the complex heterogeneity of the pathology, in particular the new diagnosis innovation and novel therapy.
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Program
- Amyloid composition
- Classification and epidemiology
- AL amyloidosis
- AA amyloidosis
- Familial amyloidosis
- Dialysis related amyloidosis (A‚2M)
- Cerebral amyloidosis
- Senile cardiac amyloidosis
- Identifying the patient with amyloidosis:
- history and examination;
- laboratory tests;
- other investigations.
- Therapy
International speaker:
Massimo Tabaton (MD, University of Genova)
The most famous amyloidosis: Alzheimer’s disease
Suggested readings and bibliography
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