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Dott. Enrico Marco Heffler

  • Phd: 25th cycle
  • Matriculation number: 276359

Contacts

Supervisor

Giovanni Rolla

Curriculum vitae

Curriculum Vitae

Research activities

Airway inflammation; Allergy; Asthma; Rhinitis; Nasal Polyposis; Vasculitis

1. Guida G, Nebiolo F, Heffler E, Bergia R, Rolla G: Anaphylaxis after a horse bite. Allergy 2005;60:1088-1089.

2. Rolla G, Heffler E, Guida G, Bergia R, Bucca C: Exhaled NO in diffuse alveolar haemorrhage. Thorax 2005;60:614-615.

3. Rolla G, Heffler E, Bommarito L, Bergia R, Ferrero N: [Exhaled nitric oxide as a marker of diseases]. Recenti Prog Med 2005;96:634-640.

4. Heffler E, Guida G, Marsico P, Bergia R, Bommarito L, Ferrero N, Nebiolo F, De Stefani A, Usai A, Bucca C, Rolla G: Exhaled nitric oxide as a diagnostic test for asthma in rhinitic patients with asthmatic symptoms. Respir Med 2006;100:1981-1987.

5. Rolla G, Nebiolo F, Guida G, Heffler E, Bommarito L, Bergia R: Level of exhaled nitric oxide during human anaphylaxis. Ann Allergy Asthma Immunol 2006;97:264-265.

6. Rolla G, Bommarito L, Heffler E, Guida G, Ferrero N, Bergia R, Badiu I, Nebiolo F: Exhaled nitric oxide in asthma. Ital J Allergol Clin Immunol 2006;16:141-50.

7. Rolla G, Guida G, Heffler E, Badiu I, Bommarito L, De Stefani A, Usai A, Cosseddu D, Nebiolo F, Bucca C: Diagnostic classification of persistent rhinitis and its relationship to exhaled nitric oxide and asthma: a clinical study of a consecutive series of patients. Chest 2007;131:1345-1352.

8. Bommarito L, Migliore E, Bugiani M, Heffler E, Guida G, Bucca C, de Marco R, Rolla G: Exhaled Nitric Oxide in a Population Sample of Adults. Respiration 2007;

9. Rolla G, Tartaglia N, Motta M, Ferrero N, Bergia R, Guida G, Heffler E: Warning nonrespiratory symptoms in asthma: catastrophic abdominal involvement in a case of Churg-Strauss syndrome. Ann Allergy Asthma Immunol 2007;98:595-597.

10. Heffler E, Guida G, Badiu I, Nebiolo F, Rolla G: Anaphylaxis after eating italian pizza containing buckwheat as the hidden allergen. J Invest Allerg Clin Immunol 2007;17:261-263.

11. Heffler E, Berry M, Pavord ID: TNF-alpha: a promising therapeutic target for asthma? Biodrugs 2007;21:345-349.

12. Rolla G, Guida G, Heffler E: Churg-Strauss syndrome: still a clinical challenge? Exp Rev Clin Immunol 2007;3:833-837.

13. Rolla G, Heffler E, Bommarito L, Guida G, Badiu I, Bergia R, Marsico P, Pizzimenti S, Nebiolo F: Exhaled nitric oxide in persistent rhinitis with or without lower airway involvement: a review of the literature. J Breath Research 2007:2

14. Guida G, Vallario A, Stella S, Boita M, Circosta P, Mariani S, Prato G, Heffler E, Bergia R, Sottile A, Rolla G, Cignetti A. Clonal CD8+ TCR-Vbeta expanded populations with effectory memory phenotype in Churg Strauss Syndrome. Clin Immunol 2008;128:94-102.

15. Pizzimenti S, Bugiani M, Piccioni P, Heffler E, Carosso A, Guida G, Rolla G. Exhaled nitric oxide measurements: correction equation to compare hand-held device to stationary analyzer. Respir Med 2008 Jun 27.

16. Bommarito L, Guida G, Heffler E, Badiu I, Nebiolo F, Usai A, De Stefani A, Rolla G. Nasal nitric oxide in suspect rhinosinusitis. Ann Allergy Asthma Immunol 2008;101:358-362.

17. Rolla G, Bruno M, Bommarito L, Heffler E, Ferrero N, Petrarulo M, Bagnis C, Bugiani M, Guida G. Breath analysis in patients with end-stage renal disease: effect of haemodialysis. Eur J Clin Invest 2008;38:728-733

18. Heffler E, Nebiolo F, Pizzimenti S, Ferlini M, Marchese C, Rolla G. Occupational asthma due to Neurospora sitophila sensitization in a coffee dispenser service operator. Ann Allergy Asthma Immunol 2009;102:168-169.

19. Asero R, Antonicelli L, Arena A, Bommarito L, Caruso B, Crivellaro M, De Carli M, Della Torre E, Della Torre F, Heffler E, Lodi Rizzini F, Longo R, Manzotti G, Marcotulli G, Melchiorre A, Minale P, Morandi P, Moreni B, Moschella A, Murzilli F, Nebiolo F, Poppa M, Randazzo S, Rossi G, Senna GE. "EPIDEMAAITO": features of food allergy in italian adults attending allergy clinics. A multicenter study. Clin Exp Allergy 2009;39:547-555.

20. Asero R, Antonicelli L, Arena A, Bommarito L, Caruso B, Colombo G, Crivellaro M, De Carli M, Della Torre E, Della Torre F, Heffler E, Lodi Rizzini F, Longo R, Manzotti G, Marcotulli G, Melchiorre A, Minale P, Morandi P, Moreni B, Moschella A, Murzilli F, Nebiolo F, Poppa M, Randazzo S, Rossi G, Senna GE. Causes of Food-Induced Anaphylaxis in Italian Adults: A Multi-Centre Study. Int Arch Allergy Immunol 2009;150:271-277.

21. Nebiolo F, Bergia R, Bommarito L, Bugiani M, Heffler E, Carosso A, Castiglioni G, Guida G, Badiu I, Pizzimenti S, Mietta S, Ferrero N, Rolla G. Arterial hypertension prolongs chronic urticaria. Ann Allergy Asthma Immunol 2009:103(5):407-10.

22. Guida G, Culla B, Scirelli T, Bellone G, Sciascia S, Brussino L, Novero D, Palestro G, Heffler E, Gavarotti P, Rolla G, Bucca C. Exhaled nitric oxide and nitric oxide synthase expression in Hodgkin's disease. Int J Immunopathol Pharmacol. 2009 Oct-Dec;22(4):1027-34.

23. Guida G, Rolla G, Badiu I, Marsico P, Pizzimenti S, Bommarito L, De Stefani A, Usai A, Bugiani M, Malinovschi A, Bucca C, Heffler E. Determinants of exhaled nitric oxide in chronic rhinosinusitis. Chest 2010: 137(3):658-64.

24. Asero R, Antonicelli L, Arena A, Bommarito L, Caruso B, Colombo G, Crivellaro M, De Carli M, Della Torre E, Della Torre F, Heffler E, Lodi Rizzini F, Longo R, Manzotti G, Marcotulli M, Melchiorre A, Minale P, Morandi P, Moreni B, Moschella A, Murzilli F, Nebiolo F, Poppa M, Randazzos S, Rossi G, Senna GE. Epinephrine autoinjector prescription in food-allergic adults: symptom-based only or allergen-based also? An Italian multi-centre study. Eur Ann Allergy Clin Immunol. 2010;42(1):25-31.

25. Heffler E, Nebiolo F, Asero R, Guida G, Badiu I, Pizzimenti S, Marchese C, Amato S, Mistrello G, Canaletti F, Rolla G. Clinical manifestations, co-sensitizations, and immunoblotting profiles of buckwheat-allergic patients.Allergy. 2011 Feb;66(2):264-70.

26. Brussino L, Badiu I, Sciascia S, Bugiani M, Heffler E, Guida G, Malinovschi A, Bucca C, Rolla G. Oxidative stress and airway inflammation after allergen challenge evaluated by exhaled breath condensate analysis. Clin Exp Allergy. 2010 Nov;40(11):1642-7

27. Rolla G, Malinovschi A, Badiu I, Heffler E, Petrarulo M, Bucca C, Brussino L. The increase in exhaled NO following allergen challenge is not associated with airway acidification. Eur J Clin Invest. 2011 Apr;41(4):411-6.

28. Bucca CB, Bugiani M, Culla B, Guida G, Heffler E, Mietta S, Moretto A, Rolla G, Brussino L. Chronic cough and irritable larynx. J Allergy Clin Immunol. 2011 Feb;127(2):412-9.

29. Malinovschi A, Pizzimenti S, Sciascia S, Heffler E, Badiu I, Rolla G. Exhaled breath condensate nitrates, but not nitrites or FENO, relate to asthma control. Respir Med. 2011 Jul;105(7):1007-13.

30. Bucca CB, Culla B, Guida G, Sciascia S, Bellone G, Moretto A, Heffler E, Bugiani M, Rolla G, Brussino L. Unexplained chronic cough and vitamin B-12 deficiency. Am J Clin Nutr. 2011 Mar;93(3):542-8.

31. AAITO-IFIACI Anisakis Consortium.(Heffler E et al.). Anisakis hypersensitivity in Italy: prevalence and clinical features: a multicenter study.Allergy. 2011 Dec;66(12):1563-9.

32. Manzotti G, Hilger C, Heffler E, Rolla G. Chronic papular urticaria due to pigeon ticks in an adult. Eur J Dermatol. 2011 Aug 20. [Epub ahead of print]

33. Losappio L, Heffler E, Contento F, Cannito C, Rolla G. Thunderstorm-related asthma epidemic owing to Olea Europaea pollen sensitization. Allergy. 2011 Nov;66(11):1510-1.

34. Skevaki CL, Maggina P, Santos AF, Rodrigues-Alves R, Antolin-Amerigo D, Borrego LM, Bretschneider I, Butiene I, Couto M, Fassio F, Gardner J, Xatzipsalti M, Hovhannisyan L, Hox V, Makrinioti H, O Neil SE, Pala G, Rudenko M, Santucci A, Seys S, Sokolowska M, Whitaker P, Heffler E. The 10th anniversary of the Junior Members and Affiliates of the European Academy of Allergy and Clinical Immunology. Pediatr Allergy Immunol. 2011 Dec;22(8):754-757

35. E. Heffler, P.L. Minciullo, F. F assio, F.W. R ossi, M. Patafi, M. Mondino, I. Badiu, G. Guida on the behalf of Junior Members working group of Italian Society of Allergy and Clinical Imunology (SIAIC). Pertinence of requested allergy consultations for suspected food allergy/intolerance. A Junior Members working group of Italian Society of Allergy and Clinical Immunology (SIAIC) multicenter study. Ital J Allergol Clin Immunol 2011.

36. Rolla G, Heffler E. Aspirin exacerbated asthma: avoiding challenge is still challenging! Int Arch Allergy Immunol 2012 [Epub ahead of print]

37. Moscato G, Pala G, Barnig C, De Blay F, Del Giacco SR, Folletti I, Heffler E, Maestrelli P, Pauli G, Perfetti L, Quirce S, Sastre J, Siracusa A, Walusiak-Skorupa J, Gerth van Wjik R. EAACI consensus statement for investigation of Work-Related Asthma in non-specialized centres. Allergy 2012[Epub ahead of print].

38. Badiu I, Geuna M, Heffler E, Rolla G. Hypersensitivity reaction to human papillomavirus vaccine due to polysorbate 80. BMJ Case Rep 2012 [in press].

39. Boita M, Rolla G, Mallone R, Martinuzzi E, Heffler E, Circosta P, Elia A, Cignetti A, Guida G. Expression of NKG2D and CD107 in CD8+ effector memory lymphocytes in Churg-Strauss syndrome. Clin Exp Rheumatol 2012 [in press].

BOOK CHAPTERS: 

Rolla G, Boita M, Heffler E, Guida G. “Churg-Strauss syndrome: clinical and pathogenetic approach to therapy” in “Advances in the diagnosis and treatment of vasulitis” (ISBN: 978-953-307-786-4.

Last update: 04/03/2014 15:16
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